The reigning Paris Masters champion beat world no.34 Gilles Muller 6-3, 6-4 and next faces no.14 seed Grigor Dimitrov (Thursday).
Nole is no.1 seed and will open his quest for a fifth title in Bercy in the second round against world no.34 Gilles Muller from Luxembourg.
Novak’s quest for a fourth Shanghai Rolex Masters crown is over after a surprise 4-6, 4-6 semi-final defeat to Roberto Bautista Agut.
Defending champion remained on course for a fourth Shanghai Rolex Masters crown as he beat Mischa Zverev 3-6, 7-6 (4), 6-3.
Novak reached the last eight defeating Canada’s Vasek Pospisil 6-4, 6-4. He next faces German qualifier Mischa Zverev (ATP #110).
Nole began his title quest at the ATP Masters 1000 event with a comfortable 6-3, 6-3 victory over world no. 50 Fabio Fognini.
Defending champion will open quest for his 31st Masters crown in R2 against Fabio Fognini (ITA #43).
The six-time titlist owns a perfect 29-0 record at the ATP World Tour 500 event, taking place at the National Tennis Center in Beijing, from October 3-9.
The world no.1 will defend four ATP titles from October 3 to November 20: Beijing, Shanghai, Paris and the ATP World Tour Finals in London.
Serbia will face Russia in a home tie in the first round on 3-5 February 2017.