Novak's US Open title defence came to a halt on Sunday when the Serb retired from his fourth-round match against Stan Wawrinka. The Swiss led, 6-4, 7-5, 2-1, when the top seed stopped due to a left shoulder injury. They were facing off for the first time since the 2016 US Open final.
The defending champion cruised through his fourth round match with a 6-3, 6-2, 6-3 victory over Ugo Humbert in one hour and 42 minutes, reaching the last eight of a major for the 45th time. He goes on to face no.21 seed David Goffin (5-1 H2H) on Wednesday.
Novak returned to the Australian Open quarterfinals for the 10th time in 15 years with a hard-fought 6-4, 6-7 (5), 6-2, 6-3 triumph over 15th seed Daniil Medvedev
The sixth seed needed two hours to progress to the US Open last 8, beating Joao Sousa 6-3, 6-4, 6-3 on Arthur Ashe Stadium. He will next face John Millman (AUS)
Novak completed efficient 6-4, 6-2, 6-2 victory over unseeded Karen Khachanov to set up a last eight meeting with 24th seed Kei Nishikori. The match lasted one hour and 45 minutes.
Nole reached his 12th French Open quarter-final with a 6-3, 6-4, 6-2 win over Spain's Fernando Verdasco on Chatrier. The victory was his 200th triumph on clay courts. Next up for Novak is world no.72 Marco Cecchinato on Tuesday
Three-time former champion beat Adrian Mannarino 6-2, 7-6 (5), 6-4 to move into his ninth Wimbledon quarter-final.