Novak completed the 2016 season with a 65-9 W/L record and seven titles won, and finished year as no. 2 for the second time in his career.
Sunday’s contest between Novak and Andy Murray will be the first occasion in history that the year-end no.1 ranking is on the line at the title-match of the season finale.
The defending champion kept up the pressure in the race for the year-end no.1 ranking with a convincing 6-1, 6-2 win over Belgian David Goffin on Thursday.
Nole continued his bid for a fifth consecutive WTFs title with a 7-6 (6), 7-6 (5) win over Milos Raonic.
Novak won his opening match at the Barclays ATP World Tour Finals, rallying to beat Dominic Thiem 6-7(10), 6-0, 6-2 on Sunday.
The world’s biggest indoor tournament begins on Sunday, November 13, at the O2 Arena in London.
The world no.1 will defend four ATP titles from October 3 to November 20: Beijing, Shanghai, Paris and the ATP World Tour Finals in London.
In his 10th appearance at the Barclays ATP World Tour Finals, world no.1 will attempt to win a record-tying sixth title.
The American ended Novak’s remarkable Grand Slam winning run, downing the top seed and defending champion 7-6 (6), 6-1, 3-6, 7-6 (5).
Nole captured his 30th straight Grand Slam win beating Frenchman Adrian Mannarino 6-4, 6-3, 7-6 (5).