Novak continued his quest for a fifth Paris Masters title with a 4-6, 6-2, 6-3 win over Grigor Dimitrov.
Nole is no.1 seed and will open his quest for a fifth title in Bercy in the second round against world no.34 Gilles Muller from Luxembourg.
The world no.1 will defend four ATP titles from October 3 to November 20: Beijing, Shanghai, Paris and the ATP World Tour Finals in London.
Novak beat Andy Murray 3-6, 6-1, 6-2, 6-4 to complete the career Grand Slam, and became just the eighth man to accomplish the feat.
Novak recorded a 7-5, 6-3, 6-4 win over Steve Darcis in the second round action at Roland Garros on Thursday.
The second Grand Slam of the season, the Roland Garros, is taking place in Paris, from May 22 to June 5, 2016.
After winning Doha, the Australian Open and the first two Masters events in 2016, Novak is full of confidence ahead of the European clay-court swing.
The world no.1 claimed a record fourth BNP Paribas Masters title on Sunday with a 6-2, 6-4 victory over no.2 seed Andy Murray.
Nole is through to his 14th tour-level final of the season after beating Stan Wawrinka 6-3, 3-6, 6-0 in the semi-finals of the BNP Paribas Masters.
Nole came up against his toughest test this week, but prevailed to clinch a 7-6 (3), 7-6 (8) victory in two hours and seven minutes.