Top seed recorded his 70th career French Open match win as he crushed Lithuanian Ricardas Berankis 6-1, 6-2, 6-2. Novak will look to continue his pursuit of a second Roland Garros title when he plays Daniel Elahi Galan (COL, LL) in the third round on Saturday.
The top seed booked his place in the Dubai Duty Free Tennis Championships last eight, following a convincing 6-3, 6-1 win over German Philipp Kohlschreiber. For a spot in the ATP 500 event semi-finals, Novak will face no.7 seed Karen Khachanov.
Top-seeded Novak rallied from 3-5 down in the first set to beat French lucky loser Corentin Moutet 7-6, 6-4 on Wednesday, kicking off his quest for a fifth Rolex Paris Masters title.
Novak defeated the big hitting Argentine 6-4, 7-6 (3), 6-1 to progress in two hours and 15 minutes under the Arthur Ashe Stadium roof. Next up for the top seed is Denis Kudla (USA, ATP #111).
Defending champion advanced into the last 16 at the Western & Southern Open on Tuesday, following a 7-5, 6-1 win over world no.45 Sam Querrey. The match lasted one hour and 18 minutes.