Novak fell to his Davis Cup teammate Janko Tipsarevic 6-7(2), 3-6 in the quarter-finals of the Mutua Madrid Open on Friday. He will next play at the Internazionali BNL d’Italia taking place at Foro Italico from May 13 to May 20.
Defending champion secured his place in the last eight at the Mutua Madrid Open, defeating Swiss Stanislas Wawrinka 7-6(5), 6-4.
The top seed overcame second-round test against Daniel Gimeno-Traver, winning in three sets 6-2, 2-6, 6-3, to progress on the new blue clay at the ATP World Tour Masters 1000 event.
The world no.1 arrived in Madrid on Wednesday with a 24-3 record on the season. He will defend his title at the second ATP World Tour Masters 1000 event on clay in 2012, taking place from May 6 till May 13.
Less than a year after lifting his first Madrid Masters trophy on the Manolo Santana Stadium Centre Court, Novak returns to the venue as the world no.1.